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Md. Mustak Khan

MS (Thesis) Student, Department of Biochemistry and Molecular Biology , University of Chittagong

Resources and Tools


 Literature Review Tools

  • Anara: An AI tool for literature reviews that simplifies reading, extracts key insights, enhances writing, and guides you through complex topics with ease.
  • ScienceOpen: A free search engine for research papers with citation metrics, altmetrics, and a user-friendly design for exploring scholarly works.
  • Semantic Scholar: An AI-powered platform for discovering and analyzing academic papers, offering deep insights into scholarly literature.
  • SciSpace: A research tool with 270+ million papers and an AI assistant, Copilot, providing summaries, explanations, and answers to aid comprehension.
  • PICO Portal: An AI tool designed to streamline systematic reviews by predicting the most relevant articles based on your criteria, reducing the number of studies you need to screen.
  • Elicit: An AI research assistant that helps in literature review by finding relevant papers, summarizing findings, and extracting key information to answer specific research questions.
  • Research Rabbit: A tool that allows researchers to create collections of papers and visualize the connections between them, aiding in the discovery of related work and the development of comprehensive literature reviews. 
  • Consensus: An AI-powered search engine that finds and summarizes research papers, helping users quickly understand the consensus in scientific literature on a given topic.

Free Courses on Research Methods, Manuscript Writing, and Publishing

Find Journer

  • JANE (Journal/Article Name Estimator): A tool that helps you find the most relevant journals for your research based on article titles or abstracts.
  • Clarivate Master Journal List: A comprehensive list of journals indexed by Clarivate, offering essential information for journal selection.
  • Scopus Journal Comparison: Allows you to compare journals indexed in Scopus based on various metrics like impact factor and citation counts.
  • Jot (Journal Targeter): A tool to help you identify the best journals for submitting your manuscript based on keywords or topics.
  • Elsevier Journal Finder: Helps you find Elsevier journals that match your research topics and manuscript.
  • Taylor & Francis Journal Suggester: This tool suggests journals from Taylor & Francis based on the title and abstract of your manuscript.
  • Think. Check. Submit: A resource to help you evaluate the trustworthiness of journals and avoid predatory publishers.
  • Wiley Journal Finder: A tool that helps you find Wiley journals by matching your manuscript with relevant journals.
  • Cabell's: Provides a directory of journals and their evaluation metrics, helping you find suitable journals for your research.
  • Journal Evaluation Tool: A tool for evaluating journals based on multiple performance metrics and journal reputation.
  • Sage Journal Recommender: Suggests Sage journals that are a good fit for your research topic using your manuscript title and abstract.

R Package for Data Analysis and Visualization

  • dplyr: A package for data manipulation, offering functions like filtering, selecting, and summarizing data. Part of the tidyverse.
  • tidyr: Focuses on tidying data, such as reshaping and separating columns. Works well with other tidyverse packages. 
  • Tidyverse: A collection of R packages (e.g., ggplot2, dplyr, tidyr, purrr) for consistent data analysis and visualization.
  • gtsummary & gt: Used for creating customizable summary tables for data frames and statistical models. 
  • ggplot2: A powerful visualization package implementing the "grammar of graphics" to create complex plots. 
  • hrbrthemes: Enhances ggplot2 plots with additional themes, color palettes, and customization options. 
  • RColorBrewer & viridis: Provide color palettes for data visualization, ideal for maps and charts. 
  • Heatmaply: Creates interactive heatmaps with customization options.

Data Science Tools 

  • NumPy: Foundation for scientific computing, offering support for multidimensional arrays and mathematical operations.
  • Pandas: Simplifies data wrangling and analysis, providing powerful tools for handling structured data.
  • Matplotlib: Used for creating static, basic data visualizations.
  • Seaborn: Enhances Matplotlib with advanced statistical visualizations and attractive aesthetics.
  • Plotly: Enables interactive and dynamic data visualizations.
  • researchpy: data and performs statistical tests efficiently.
  • Dask: Handles big data analysis with parallel computing support.
  • scikit-learn: A versatile library for machine learning, offering tools for classification, regression, and clustering.
  • scikit-image: Provides tools for image manipulation, especially useful in life sciences.

Bioinformatics Tools, Software, and Datasets

Sequence Retrieval and Analysis:
  • NCBI Database: Provides access to genomic and protein sequence data for various organisms.
  • EMBOSS Stretcher:: Aligns nucleotide or protein sequences using dynamic programming.
  • PROSITE: Identifies protein motifs and conserved functional domains.
Homology Modeling:
  • Modeller v9.26: Constructs 3D protein structures based on homologous templates.
  • Swiss-Model: Automates template selection and homology-based structure modeling.
Model Evaluation and Energy Minimization:
  • YASARA: Performs energy minimization and molecular simulations.
  • SAVES: Assesses stereochemistry and structure validation of protein models.
  • Superpose: Compares 3D structural alignments of proteins.
Visualization and Structural Analysis: 
  • PyMOL: Visualizes, analyzes, and animates 3D molecular structures for proteins, ligands, and complexes, producing publication-quality images  
Active Site Prediction:
Ligand Design:
  • Marvin JS: Facilitates chemical structure drawing and editing.
Pharmacophore Modeling and Virtual Screening:
  • LigandScout: Generates pharmacophore models for drug discovery.
  • ZINCPHARMER: Screens ligand databases for potential drug candidates.
Pharmacodynamics and ADMET Analysis:
  • SwissADME: Predicts pharmacokinetics and drug-likeness of molecules.
  • ADMETSAR-2.0: Evaluates absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties.
Molecular Docking:
  • AutoDock Vina: Performs ligand-protein docking simulations.
  • PyRx: Integrates AutoDock and AutoDock Vina for virtual screening and docking through an intuitive graphical interface. 
  • PatchDockConducts molecular docking through geometric shape complementarity.
  • FireDock: Refines docking results with energy-based optimization.
Molecular Dynamics Simulation:
  • GROMACS: Runs high-performance molecular dynamics simulations.
Analysis of MD Trajectories:
  • VMD: Visualizes and analyzes molecular dynamics trajectories.
Pocket Dynamics Analysis:
Density Functional Theory (DFT) Calculation:
  • Spartan 14: Computes electronic properties like HOMO/LUMO analysis.
Protein Annotation and Functional Prediction:
  • Pfam: Detects conserved protein families and domains.
  • SignalP: Predicts signal peptides for protein secretion.
Epitope Prediction and Vaccine Design:
  • IEDB Tools: Identifies MHC-binding and B-cell epitopes for vaccine design.
Codon Optimization and In-Silico Cloning:
  • SnapGene: Simulates in-silico DNA cloning and plasmid construction.
mRNA Structure Prediction:
  • RNAfold: Predicts secondary structures of RNA sequences.

Free Courses and Tutorials for Bioinformatics  

C. elegans Databases & Resources

WormBase: Central database for C. elegans genetics, genomics, phenotypes, and annotations.
WormBook: Open-access, peer-reviewed resource on C. elegans biology and research methods.
WormAtlas: Anatomical and structural reference with detailed imaging and connectivity maps.
Caenorhabditis elegans Natural Diversity Resource (CeNDR / CaeNDR): Repository for wild isolates, natural variation, and genome-wide association mapping.
Caenorhabditis Genetics Center (CGC): Provides C. elegans strains, stocks, and genetic resources.
OpenWorm: Computational project simulating C. elegans anatomy, connectome, and behavior.
Textpresso for C. elegans: Literature search engine for full-text publications on C. elegans.
C. elegans Connectome Datasets: Neural wiring and connectivity data for the full worm nervous system. 

Research & Scientific Databases 

Genomics Databases 
  • NCBI GenBank: A comprehensive nucleotide sequence database with annotated genetic information.
  • Ensembl Genome Browser: Provides genome data, annotations, and comparative genomics tools.
  • UCSC Genome Browser: Interactive genome visualization with integrated annotation tracks.
  • DDBJ: DNA Data Bank of Japan, part of the international nucleotide sequence collaboration.
  • 1000 Genomes Project: A large-scale catalog of human genetic variation across populations.  
Transcriptomics Databases
  • GEO: NCBI repository for functional genomics and transcriptomics datasets.
  • ArrayExpress: EMBL-EBI’s archive of functional genomics experiments and gene expression data.
  • SRA: Sequence Read Archive for high-throughput sequencing data storage.
  • Expression Atlas: Explores gene expression across tissues, conditions, and organisms.
  • GTEx: Genotype-Tissue Expression project linking genetic variation with tissue-specific expression. 
Proteomic Databases
  • UniProt: Central hub for protein sequences and functional annotation.
  • PDB: Protein Data Bank containing 3D structural data of biomolecules.
  • Pfam: Database of protein families and domains with sequence alignments.
  • STRING: Protein–protein interaction networks from experiments and predictions.
  • PRIDE: Repository for proteomics mass spectrometry datasets.
Metabolomics Databases
  • HMDB: Human Metabolome Database for small-molecule metabolites.
  • MetaboLights: EBI resource for metabolomics experiments and studies.
  • KEGG Metabolomics: Pathway maps for metabolism and biochemical networks.
  • LipidMaps: Specialized database for lipid structures and pathways.
  • Reactome: Curated database of biological pathways and reactions.
Genetic Variation Databases
  • dbSNP: Archive of simple genetic variations such as SNPs.
  • ClinVar: Clinical relevance of genetic variants linked to diseases.
  • gnomAD: Genome Aggregation Database with allele frequency data.
  • COSMIC: Catalog of somatic mutations in human cancer.
  • dbVar: Database of large-scale genomic structural variations. 
Cancer Databases
  • TCGA: The Cancer Genome Atlas, a molecular characterization of cancer.
  • ICGC: International Cancer Genome Consortium providing global cancer datasets.
  • cBioPortal: Interactive platform for exploring cancer genomics data.
  • Oncomine: Gene expression resource for oncology research.
  • COSMIC: Database of cancer mutations (also in variation databases). 
Health & Biomedical Data
  • UK Biobank: Large-scale biomedical database with genetic and health data.
  • DHS Program: Demographic and Health Surveys for global population health.
  • World Values Survey (WVS): Global survey on social, cultural, and health-related values.
  • GHDx: Global Health Data Exchange with worldwide health datasets.
  • MICS (UNICEF): Multiple Indicator Cluster Surveys for child and maternal health. 
Drug Discovery & Chemical Databases
  • ChEMBL: Bioactive drug-like compounds with activity data.
  • DrugBank: Drug and drug-target information database.
  • PubChem: Public database of chemicals and their biological activities.
  • BindingDB: Binding affinities for biomolecular interactions and drug discovery. 
Plant Databases
  • TAIR: Arabidopsis thaliana genome and functional biology database.
  • Gramene: Comparative genomics resource for plants and crops.
  • PlantGDB: Plant genome resources and gene annotations.
  • Phytozome: Comparative platform for green plant genomics.
  • BAR: Bio-Analytic Resource for plant gene expression and visualization.
Microbiology & Virology Databases 
  • ViPR: Virus Pathogen Resource with genome and analysis tools.
  • PATRIC: Pathosystems Resource for bacterial pathogens.
  • IMG/M: Integrated Microbial Genomes & Microbiomes data platform.
  • MG-RAST: Metagenomics analysis server for microbial communities.
  • GISAID: Global database for influenza and SARS-CoV-2 genomic data. 
Structural Biology & Molecular Modeling Databases 
  • CATH: Classification of protein domain structures.
  • SCOP: Structural Classification of Proteins based on hierarchies.
  • ModBase: Comparative protein structure models.
  • EMDB: Electron Microscopy Data Bank for 3D structures.
  • SwissSidechain: Database for molecular modeling in drug design. 
 Clinical & Epidemiology Databases 
  • ClinicalTrials.gov: Registry of clinical trials worldwide.
  • WHO Clinical Trials Registry: International clinical trial registration platform.
  • SEER: Cancer incidence and survival data in the U.S.
  • GHDx: Global health metrics and epidemiological datasets.
  • BioLINCC: Access to clinical and epidemiologic study resources. 

Biological Illustration Tools

  • BioArt: Hosted by the National Institute of Allergy and Infectious Diseases (NIAID), BioArt provides over 2,000 science and medical visuals, including vectors, icons, and brushes, created by professional illustrators. 
  • Bioicon: Bioicon offers a collection of high-quality biological icons and illustrations to enhance scientific presentations and educational materials.
  • BioRender: BioRender's scientific illustration software includes an activity sheet with editable lab icons, enabling users to create publication-quality figures using pre-made icons and templates. 
  • SciDraw: SciDraw is a platform that offers a variety of scientific drawings, including vectors of cells, animals, and laboratory equipment, contributed by the scientific community.
  • Servier Medical Art (SMART): It offers over 3,000 free, high-quality medical illustrations suitable for publications and presentations. The collection encompasses various medical specialties, including anatomy, cellular biology, and general medical items.
  • Reactome: Reactome is a free, open-source, curated, and peer-reviewed pathway database that provides insights into molecular processes and pathways in human biology.
  • LabIcons: LabIcons offers free drawings of laboratory objects to improve knowledge communication in science and education, including clip arts of microcentrifuge tubes, plasticware, instruments, equipment, and glassware.

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